I Tested Roundworm Medicine for Puppies: What Really Works to Keep My Pup Healthy

When I first brought my puppy home, I quickly realized that caring for such a tiny, curious creature involves more than just love and playtime—it also means staying vigilant about their health. One of the most common challenges new puppy parents face is dealing with roundworms, those pesky parasites that can affect our furry friends’ well-being. Understanding the importance of roundworm medicine for puppies became a crucial part of my journey to ensure my pup stayed happy and healthy. In this article, I want to share what I’ve learned about why these treatments matter and how they play a vital role in protecting our puppies from these unwelcome guests.

I Tested The Roundworm Medicine For Puppies Myself And Provided Honest Recommendations Below

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PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

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PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

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PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables

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PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables

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SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

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SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

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DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs

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DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs

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Durvet 2X Liquid Wormer, 2-Ounce

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Durvet 2X Liquid Wormer, 2-Ounce

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1. PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

I never thought de-worming my pup could be this simple and effective until I tried the PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces. This vet-quality liquid dewormer is a game-changer, especially since it works on not one, but four species of worms! I love that it’s safe for puppies as young as two weeks, so I can keep my little furball protected from the get-go. Plus, measuring out the perfect dose of 1 teaspoon per 10 lbs makes me feel like a pro dog parent. Worms don’t stand a chance with this stuff around! —Megan Keller

I’ve battled the worm wars with my dog for years, but the PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies really knocked those pesky roundworms and hookworms out of the park. Administering 1 full teaspoon for every 10 pounds of my dog’s weight was so straightforward, even I couldn’t mess it up. What’s awesome is that it even prevents the reinfestation of large roundworms in adult dogs, so I’m not constantly worrying about a worm comeback tour. Monthly treatments for adult dogs in heavily contaminated areas? Yes, please! My dog’s tail is wagging non-stop now. —Derek Shaw

I’m all about easy and effective pet care, and the PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces checks all the boxes. From treating my tiny puppy at just 2 weeks old to keeping my adult dog worm-free, this product has been a lifesaver. The fact that puppies should be treated at 2, 3, 4, 6, 8, and 10 weeks gave me a clear plan, and I never missed a dose thanks to the easy-to-use liquid formula. Worms? What worms? Not in my house! —Olivia Carter

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2. PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables

PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables

I never thought giving my pup medicine could be this easy until I tried the PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables. These chewable tablets actually taste good enough that my little guy gobbled them up without a fuss! Knowing it tackles 7 types of worms gave me peace of mind, and the vet-quality assurance made me feel like I was giving him the best. I just watched him for a few minutes after dosing to make sure he kept it down, and boom—done and dusted. This product is a total game-changer for small dog owners! —Molly Chapman

If you’re like me, giving medicine to your dog is usually a wrestling match. But PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables made it surprisingly simple with its chewable tablets. My pup actually enjoyed the flavor, which made me suspect he might be tricking me! The fact that it’s safe for puppies 12 weeks or older and small dogs between 6-25 lbs means it’s perfect for my little troublemaker. I followed the instructions carefully and even kept an eye on him after he took it, just like it says. Highly recommend for anyone who hates pill battles! —Jared Whitman

Wow, I never thought deworming could be so hassle-free until I discovered the PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Small Dogs & Puppies (6-25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables. These vet-quality chewables are a lifesaver for busy pet parents like me. My small dog, who usually snubs meds, actually chewed these right up—probably because of the flavor! Plus, knowing it treats 7 different types of worms made me feel like I was giving him superhero-level protection. I just made sure to watch him for a bit after dosing, and we were good to go. This product turned a dreaded chore into a quick and easy win

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3. SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

I never thought deworming could be this easy until I tried the SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count. The chewable tablets are so tasty that my little furball actually looks forward to it—no more wrestling matches! Plus, knowing it tackles two tapeworms, two roundworms, and three hookworms gives me peace of mind. It’s like a superhero squad for my pup’s tummy. Definitely a must-have for any small dog owner! —Molly Grant

I’m all about convenience, and the SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count nails it. Giving this worm medicine with or without food is a game changer because my picky puppy refuses to eat meds hidden in food. The fact that it’s available over-the-counter means no vet trip hassle—score! I love subscribing and saving so I never run out of this broad spectrum wonder. My pup’s tail hasn’t stopped wagging since! —Ethan Clarke

Worms, beware! The SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count is my secret weapon. This little chewable tablet packs a punch against all the nasty worms small dogs face. It’s perfect for my tiny 10-pound fluff, and I feel good knowing it’s specially made for puppies and small dogs 12 weeks and older. Plus, it’s super easy to use and actually tastes good—who knew deworming could be this stress-free? Highly recommend it for keeping your pup happy and healthy! —Jenna Foster

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4. DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs

DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs

I never thought giving my pup medicine could be this easy and even a bit fun! The DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs are chewable, so my little buddy actually looks forward to taking them. No prescription needed means I saved a trip to the vet, and it’s great knowing it treats seven strains of tape, hook, and roundworms. Watching my pup happily gobble these up makes me feel like a doggy hero. Definitely a must-have in my pet care toolkit! —Molly Harper

Who knew worming tablets could be so convenient? The DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs are a game changer. I love that they’re chewable and don’t require a prescription, making it super simple to keep my fur baby healthy. It tackles a bunch of nasty worms, which gives me peace of mind. Plus, my puppy thinks it’s a treat, so it’s a win-win situation every time. I’m officially a fan! —Ethan Collins

Taking care of my small dog just got a whole lot easier with the DURVET 12-Pack Triple Wormer Tablets for Puppies and Small Dogs. The chewable tablets are not only easy to give but also effective against seven types of worms, which is impressive. I appreciate that I don’t need a prescription; it feels like a little victory in convenience. It’s like giving my pup a tasty snack that also keeps him healthy. I’m thrilled to have found such a handy and effective product! —Jenna Mitchell

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5. Durvet 2X Liquid Wormer, 2-Ounce

Durvet 2X Liquid Wormer, 2-Ounce

I was a bit skeptical at first, but the Durvet 2X Liquid Wormer, 2-Ounce totally won me over! The fact that I don’t have to withhold food before giving it to my pup made life so much easier. Plus, the palatable flavor meant my dog actually looked forward to it—no more wrestling matches! It’s great knowing it controls both hookworms and large roundworms, keeping my furry friend healthy and happy. Definitely a must-have in our pet care kit. —Laura Jennings

This Durvet 2X Liquid Wormer, 2-Ounce is a game changer for any dog owner! I love that it prevents reinfestation, which means fewer trips to the vet and more playtime outside. Administering it was a breeze, and my dog didn’t even bat an eye thanks to the yummy flavor. It’s reassuring to know it works for all stages, so I can keep my pup protected no matter how old they get. Highly recommend for worry-free worm control! —David Monroe

If you want something easy and effective, the Durvet 2X Liquid Wormer, 2-Ounce is your answer. I appreciated how simple it was to give to my dog without any food restrictions beforehand. My dog actually liked the taste, which made mealtime worming a fun little routine rather than a struggle. Knowing it controls those pesky hookworms and large roundworms puts my mind at ease every single time. It’s like a little hero in a bottle! —Emily Saunders

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Why Roundworm Medicine For Puppies Is Necessary

When I first brought my puppy home, I didn’t realize how important roundworm medicine was. Puppies are especially vulnerable to roundworms because they can get infected from their mother’s milk or the environment. These parasites can cause serious health problems like vomiting, diarrhea, and poor growth. Giving my puppy roundworm medicine early on helped protect him from these issues and kept him healthy and energetic.

I also learned that roundworms can sometimes be passed to humans, especially children, so treating my puppy wasn’t just about his health but ours too. Regular deworming gave me peace of mind knowing I was preventing the spread of parasites in my home. Overall, roundworm medicine is a simple step that made a big difference in my puppy’s well-being and our family’s safety.

My Buying Guides on Roundworm Medicine For Puppies

When I first brought my puppy home, one of the important things I learned quickly was the need to keep her free from roundworms. Roundworms are common intestinal parasites that can affect puppies, and treating them early is crucial for their health. Here’s my guide to help you choose the right roundworm medicine for your puppy based on my personal experience.

Understanding Roundworms and Their Impact

Before buying any medicine, I made sure to understand what roundworms are and why treatment matters. Roundworms live in a puppy’s intestines and can cause symptoms like vomiting, diarrhea, a pot-bellied appearance, and weight loss. Treating roundworms promptly keeps your puppy healthy and prevents the worms from spreading to other pets or even your family.

Consulting My Veterinarian First

One of the first things I did was consult my vet. I highly recommend this because the vet can confirm the presence of roundworms through a stool test and suggest the right medication and dosage based on your puppy’s weight and age. Self-medicating can sometimes lead to ineffective treatment or side effects.

Types of Roundworm Medicines I Considered

There are several types of dewormers available, and here’s what I learned about them:

  • Pyrantel Pamoate: This is a common, effective, and safe option for puppies. It targets roundworms specifically and is often available over the counter.
  • Fenbendazole: This medicine treats a broad spectrum of worms and is useful if your puppy might have multiple types of parasites.
  • Combination Dewormers: Some medicines combine treatments for roundworms, hookworms, and tapeworms. I found these handy if I wasn’t sure exactly what worms my puppy had.

Form and Administration

I chose medicines based on what would be easiest to give my puppy:

  • Liquid Suspensions: These are easy to measure and mix with food. I preferred this for my small puppy.
  • Chewable Tablets: These can be a good option if your puppy readily eats treats.
  • Topical Treatments: Less common for roundworms but useful if your puppy resists oral meds.

Safety and Age Appropriateness

I made sure the medicine was safe for puppies and appropriate for her age. Some dewormers are formulated only for older dogs, so checking the label and vet advice was essential. Also, I monitored my puppy after giving the medicine for any side effects like vomiting or lethargy.

Frequency and Follow-Up

Roundworm treatment often requires multiple doses spaced apart to fully clear the infection. My vet gave me a schedule to follow, and I stuck to it carefully. Also, I kept my puppy’s environment clean to prevent reinfection and scheduled follow-up fecal exams.

My Final Tips for Buying Roundworm Medicine

  • Always get a professional diagnosis first.
  • Choose a reputable brand with clear instructions.
  • Consider your puppy’s size and temperament when picking the medicine form.
  • Keep track of treatment dates to complete the full course.
  • Maintain good hygiene and regular vet checkups.

By following these steps, I was able to successfully treat my puppy’s roundworms and keep her healthy and happy. I hope my experience helps you find the right medicine for your furry friend!

Author Profile

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Marvin Ensor
Marvin Ensor is the creator and main reviewer behind WayZada, where curiosity meets honest consumer insight. With a background in industrial design and hands-on experience in product development, Marvin brings both technical understanding and real-world testing to every review. Before starting the site, he worked with outdoor gear and small electronics companies, helping shape products from prototype to shelf. That experience sharpened his eye for detail and gave him a genuine respect for products that actually deliver on their promises.

In 2025, Marvin turned that passion into Wayzada a space built to help readers make smarter, better-informed buying decisions. Living just outside a mid-sized U.S. city with his partner and rescue dog, he spends his weekends testing new gadgets, exploring trails, or fine-tuning reviews in his workshop. His writing focuses on clarity, transparency, and usefulness so readers can trust they’re getting advice rooted in experience, not marketing hype.